Introduction
GLECLUBS is an algorithm for predicting cis -regulatory binding sites in a prokaryotic genome, which was described in the following paper:
Shaoqiang Zhang, Minli Xu, Shan Li, and Zhengchang Su. Genome-wide de novo prediction of cis -regulatory binding sites in prokaryotes. Nucleic Acids Research , 2009. doi:10.1093/nar/gkp248.
Validation of the predictions in E. coli K12 and B. subtilis :
Recovery of known binding sites in RegulonDB for E. coli K12
Recovery of known binding sites in DBTBS for B. subtilis
eGLECLUBS is an extended version of GLECLUBS for simultaneously predicting binding sites in a group of closely related prokaryotic genomes, which was described in the following paper:
Shaoqiang Zhang, Shan Li, Phuc T. Pham, and Zhengchang Su. Simultaneous prediction of cis -regulatory binding sites in a group of prokaryotic genomes. submitted .
Software download:
eGLECLUBS: Click here to download the eGLECLUBS package and an example of a group of firmicutes
GLECLUBS: Click here to download the GLECLUBS package
Research Funding: